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Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4

G protein coupled receptors (GPCRs) allow for the transmission of signals across biological membranes. For a number of GPCRs, this signaling was shown to be coupled to prior dimerization of the receptor. The chemokine receptor type 4 (CXCR4) was reported before to form dimers and their functionality...

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Detalles Bibliográficos
Autores principales: Pluhackova, Kristyna, Gahbauer, Stefan, Kranz, Franziska, Wassenaar, Tsjerk A., Böckmann, Rainer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094716/
https://www.ncbi.nlm.nih.gov/pubmed/27812115
http://dx.doi.org/10.1371/journal.pcbi.1005169