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Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4
G protein coupled receptors (GPCRs) allow for the transmission of signals across biological membranes. For a number of GPCRs, this signaling was shown to be coupled to prior dimerization of the receptor. The chemokine receptor type 4 (CXCR4) was reported before to form dimers and their functionality...
Autores principales: | Pluhackova, Kristyna, Gahbauer, Stefan, Kranz, Franziska, Wassenaar, Tsjerk A., Böckmann, Rainer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094716/ https://www.ncbi.nlm.nih.gov/pubmed/27812115 http://dx.doi.org/10.1371/journal.pcbi.1005169 |
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