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The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis

Classical quantitative genetic analyses estimate additive and non-additive genetic and environmental components of variance from phenotypes of related individuals without knowing the identities of quantitative trait loci (QTLs). Many studies have found a large proportion of quantitative trait variat...

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Detalles Bibliográficos
Autores principales: Huang, Wen, Mackay, Trudy F. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094750/
https://www.ncbi.nlm.nih.gov/pubmed/27812106
http://dx.doi.org/10.1371/journal.pgen.1006421