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BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development

Notch signaling plays a crucial role in controling the proliferation and differentiation of stem and progenitor cells during embryogenesis or organogenesis, but its regulation is incompletely understood. BLOS2, encoded by the Bloc1s2 gene, is a shared subunit of two lysosomal trafficking complexes,...

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Detalles Bibliográficos
Autores principales: Zhou, Wenwen, He, Qiuping, Zhang, Chunxia, He, Xin, Cui, Zongbin, Liu, Feng, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094856/
https://www.ncbi.nlm.nih.gov/pubmed/27719760
http://dx.doi.org/10.7554/eLife.18108