Cargando…

A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution

Understanding chromatin function requires knowing the precise location of nucleosomes. MNase-seq methods have been widely applied to characterize nucleosome organization in vivo, but generally lack the accuracy to determine the precise nucleosome positions. Here we develop a computational approach l...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xu, Blocker, Alexander W, Airoldi, Edoardo M, O'Shea, Erin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094857/
https://www.ncbi.nlm.nih.gov/pubmed/27623011
http://dx.doi.org/10.7554/eLife.16970