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Prevalence of alpha-1 antitrypsin deficiency and allele frequency in patients with COPD in Brazil

OBJECTIVE: To determine the prevalence of alpha 1-antitrypsin (AAT) deficiency (AATD), as well as allele frequency, in COPD patients in Brazil. METHODS: This was a cross-sectional study involving 926 COPD patients 40 years of age or older, from five Brazilian states. All patients underwent determina...

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Detalles Bibliográficos
Autores principales: Russo, Rodrigo, Zillmer, Laura Russo, Nascimento, Oliver Augusto, Manzano, Beatriz, Ivanaga, Ivan Teruaki, Fritscher, Leandro, Lundgren, Fernando, Miravitlles, Marc, Gondim, Heicilainy Del Carlos, Santos, Gildo, Alves, Marcela Amorim, Oliveira, Maria Vera, de Souza, Altay Alves Lino, Sales, Maria Penha Uchoa, Jardim, José Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094866/
https://www.ncbi.nlm.nih.gov/pubmed/27812629
http://dx.doi.org/10.1590/S1806-37562015000000180