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VPO1 mediates oxidation of LDL and formation of foam cells

Deposition of oxidized-LDL in vascular walls is essential in the initiation of atherosclerosis. Oxidation of LDL has been attributed to myeloperoxidase as its generation of potent oxidants. However, the exact mechanism of LDL oxidation and foam cell formation in atherosclerosis remains to be elucida...

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Detalles Bibliográficos
Autores principales: Yang, Youfeng, Shi, Ruizheng, Cao, Zehong, Zhang, Guogang, Cheng, Guangjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094940/
https://www.ncbi.nlm.nih.gov/pubmed/27167346
http://dx.doi.org/10.18632/oncotarget.9193