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Deficiency of myeloid-related proteins 8 and 14 (Mrp8/Mrp14) does not block inflammaging but prevents steatosis

The Mrp8 and Mrp14 proteins (calprotectin) accumulate within tissues during aging and may contribute to chronic inflammation. To address this possibility, we evaluated female calprotectin-deficient Mrp14-KO and wild-type (WT) mice at 5 and 24 months of age. However, there was no evidence that age-re...

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Detalles Bibliográficos
Autores principales: Swindell, William R., Xing, Xianying, Fritz, Yi, Diaconu, Doina, Simon, Daniel I., Ward, Nicole L., Gudjonsson, Johann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094943/
https://www.ncbi.nlm.nih.gov/pubmed/27224926
http://dx.doi.org/10.18632/oncotarget.9550