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Deficiency of myeloid-related proteins 8 and 14 (Mrp8/Mrp14) does not block inflammaging but prevents steatosis
The Mrp8 and Mrp14 proteins (calprotectin) accumulate within tissues during aging and may contribute to chronic inflammation. To address this possibility, we evaluated female calprotectin-deficient Mrp14-KO and wild-type (WT) mice at 5 and 24 months of age. However, there was no evidence that age-re...
Autores principales: | Swindell, William R., Xing, Xianying, Fritz, Yi, Diaconu, Doina, Simon, Daniel I., Ward, Nicole L., Gudjonsson, Johann E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094943/ https://www.ncbi.nlm.nih.gov/pubmed/27224926 http://dx.doi.org/10.18632/oncotarget.9550 |
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