Cargando…

Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation

Neddylation, a newly identified post-translational modification, is significant for the activity and stability of target proteins. The exact role of neddylation in the pathogenesis of inflammatory bowel disease, specifically those mediated by dendritic cells (DCs), was still rarely reported. Here, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Mengmeng, Hu, Shurong, Wang, Zhengting, Pei, Yaofei, Fan, Rong, Liu, Xiqiang, Wang, Lei, Zhou, Jie, Zheng, Sichang, Zhang, Tianyu, Lin, Yun, Zhang, Maochen, Tao, Ran, Zhong, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094951/
https://www.ncbi.nlm.nih.gov/pubmed/27224922
http://dx.doi.org/10.18632/oncotarget.9543