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Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation
Neddylation, a newly identified post-translational modification, is significant for the activity and stability of target proteins. The exact role of neddylation in the pathogenesis of inflammatory bowel disease, specifically those mediated by dendritic cells (DCs), was still rarely reported. Here, w...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094951/ https://www.ncbi.nlm.nih.gov/pubmed/27224922 http://dx.doi.org/10.18632/oncotarget.9543 |