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Copy number variations in urine cell free DNA as biomarkers in advanced prostate cancer

Genetic profiling of urine cell free DNA (cfDNA) has not been evaluated in advanced prostate cancer. We performed whole genome sequencing of urine cfDNAs to identify tumor-associated copy number variations in urine before and after initiating androgen deprivation therapy in HSPC stage and docetaxel...

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Detalles Bibliográficos
Autores principales: Xia, Yun, Huang, Chiang-Ching, Dittmar, Rachel, Du, Meijun, Wang, Yuan, Liu, Hongyan, Shenoy, Niraj, Wang, Liang, Kohli, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094965/
https://www.ncbi.nlm.nih.gov/pubmed/27127882
http://dx.doi.org/10.18632/oncotarget.9027