EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma

Enhancer of zeste homolog 2 (EZH2), a catalytic core component of the Polycomb repressive complex 2 (PRC2), stimulates the silencing of target genes through histone H3 lysine 27 trimethylation (H3K27me3). Recent findings have indicated EZH2 is involved in the development and progression of various h...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Zheng, Peng-Sheng, Yang, Wen-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094987/
https://www.ncbi.nlm.nih.gov/pubmed/27092879
http://dx.doi.org/10.18632/oncotarget.8741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094987/
https://www.ncbi.nlm.nih.gov/pubmed/27092879
http://dx.doi.org/10.18632/oncotarget.8741

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