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EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma

Enhancer of zeste homolog 2 (EZH2), a catalytic core component of the Polycomb repressive complex 2 (PRC2), stimulates the silencing of target genes through histone H3 lysine 27 trimethylation (H3K27me3). Recent findings have indicated EZH2 is involved in the development and progression of various h...

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Detalles Bibliográficos
Autores principales:	Chen, Qian, Zheng, Peng-Sheng, Yang, Wen-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094987/ https://www.ncbi.nlm.nih.gov/pubmed/27092879 http://dx.doi.org/10.18632/oncotarget.8741

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