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Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death

A critical first step in the personalized approach to cancer treatment is the identification of activated oncogenes that drive each tumor. The Identification of driver oncogenes on a patient-by-patient basis is complicated by the complexity of the cancer genome and the fact that a particular genetic...

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Detalles Bibliográficos
Autores principales: Guest, Stephen T., Kratche, Zachary R., Irish, Jonathan C., Wilson, Robert C., Haddad, Ramsi, Gray, Joe W., Garrett-Mayer, Elizabeth, Ethier, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094989/
https://www.ncbi.nlm.nih.gov/pubmed/27153554
http://dx.doi.org/10.18632/oncotarget.9147