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Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death
A critical first step in the personalized approach to cancer treatment is the identification of activated oncogenes that drive each tumor. The Identification of driver oncogenes on a patient-by-patient basis is complicated by the complexity of the cancer genome and the fact that a particular genetic...
Autores principales: | Guest, Stephen T., Kratche, Zachary R., Irish, Jonathan C., Wilson, Robert C., Haddad, Ramsi, Gray, Joe W., Garrett-Mayer, Elizabeth, Ethier, Stephen P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094989/ https://www.ncbi.nlm.nih.gov/pubmed/27153554 http://dx.doi.org/10.18632/oncotarget.9147 |
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