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Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway
Absent in melanoma (AIM2) is a member of the interferon-inducible HIN-200 protein family and is recently recognized to play an important dual role in both innate immunity and tumor pathology. However, the role of AIM2 in the development of hepatocellular carcinoma (HCC) remains to be clarified. Here...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094992/ https://www.ncbi.nlm.nih.gov/pubmed/27167192 http://dx.doi.org/10.18632/oncotarget.9154 |