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Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway

Absent in melanoma (AIM2) is a member of the interferon-inducible HIN-200 protein family and is recently recognized to play an important dual role in both innate immunity and tumor pathology. However, the role of AIM2 in the development of hepatocellular carcinoma (HCC) remains to be clarified. Here...

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Detalles Bibliográficos
Autores principales: Ma, Xiaomin, Guo, Pengbo, Qiu, Yumin, Mu, Kun, Zhu, Lihui, Zhao, Wei, Li, Tao, Han, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094992/
https://www.ncbi.nlm.nih.gov/pubmed/27167192
http://dx.doi.org/10.18632/oncotarget.9154