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TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes

TP53 mutations are frequently detected in patients with higher-risk myelodysplastic syndromes (MDS); however, the clinical impact of these mutations on the disease course of patients with lower-risk MDS is unclear. In this study of 154 lower-risk MDS patients, TP53 mutations were identified in 13% o...

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Detalles Bibliográficos
Autores principales: Belickova, Monika, Vesela, Jitka, Jonasova, Anna, Pejsova, Barbora, Votavova, Hana, Merkerova, Michaela Dostalova, Zemanova, Zuzana, Brezinova, Jana, Mikulenkova, Dana, Lauermannova, Marie, Valka, Jan, Michalova, Kyra, Neuwirtova, Radana, Cermak, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094999/
https://www.ncbi.nlm.nih.gov/pubmed/27167113
http://dx.doi.org/10.18632/oncotarget.9200