Cargando…

ER stress inducer tunicamycin suppresses the self-renewal of glioma-initiating cell partly through inhibiting Sox2 translation

Glioma-initiating cells possess tumor-initiating potential and are relatively resistant to conventional chemotherapy and irradiation. Therefore, their elimination is an essential factor for the development of efficient therapy. Here, we report that endoplasmic reticulum (ER) stress inducer tunicamyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Yang, Ge, Yuqing, Liu, Chanjuan, Zhang, Xiaobiao, Jiang, Jianhai, Wei, Yuanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095008/
https://www.ncbi.nlm.nih.gov/pubmed/27119230
http://dx.doi.org/10.18632/oncotarget.8954