Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

Unregulated growth and replication as well as an abnormal microenvironment, leads to elevated levels of stress which is a common trait of cancer. By inducing both energy and endoplasmic reticulum (ER) stress, 2-Deoxy-glucose (2-DG) is particularly well-suited to take advantage of the therapeutic win...

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Detalles Bibliográficos
Autores principales: Liu, Huaping, Kurtoglu, Metin, León-Annicchiarico, Clara Lucia, Munoz-Pinedo, Cristina, Barredo, Julio, Leclerc, Guy, Merchan, Jaime, Liu, Xiongfei, Lampidis, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095013/
https://www.ncbi.nlm.nih.gov/pubmed/27183907
http://dx.doi.org/10.18632/oncotarget.9263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095013/
https://www.ncbi.nlm.nih.gov/pubmed/27183907
http://dx.doi.org/10.18632/oncotarget.9263

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