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Sulfatide interacts with and activates integrin αVβ3 in human hepatocellular carcinoma cells

Integrin αVβ3 is a malignant driver of anchorage-independence and tumor angiogenesis, but its dysregulation in hepatocellular carcinoma (HCC) remains unclear. In this study, we observed that sulfatide significantly promoted integrin αV(ITGAV) expression and wound closure in HCC. We also noted that e...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Qi, Bing, Dong, Yi Wei, Cai, Qian Qian, Deng, Nian Hui, Chen, Qi, Li, Chao, Jin, Yu Tong, Wu, Xing Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095021/
https://www.ncbi.nlm.nih.gov/pubmed/27145276
http://dx.doi.org/10.18632/oncotarget.9095