Altered methylation of glucosylceramide synthase promoter regulates its expression and associates with acquired multidrug resistance in invasive ductal breast cancer

Overexpression of glucosylceramide synthase (GCS) increases multidrug resistance (MDR) in many cancer cells. However, its mechanism is unknown. The aim of the present study is to detect the association of methylation at the GCS gene promoter with its expression and MDR in invasive ductal breast canc...

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Detalles Bibliográficos
Autores principales: Liu, Jiannan, Zhang, Xiaofang, Liu, Aina, Zhang, Daoping, Su, Yi, Liu, Ying, You, Dong, Yuan, Leilei, Kong, Xiangshuo, Wang, Xiaodan, Sun, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095037/
https://www.ncbi.nlm.nih.gov/pubmed/27191984
http://dx.doi.org/10.18632/oncotarget.9337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095037/
https://www.ncbi.nlm.nih.gov/pubmed/27191984
http://dx.doi.org/10.18632/oncotarget.9337

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