Cargando…

JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients

BACKGROUND AND AIMS: JWA, a microtubule-associated protein (MAP) involved in apoptosis, has been identified as a suppressor of metastasis, and it affects cell migration in melanoma and its downregulation in tumor is an idependent negative prognostic factor in resectable gastric cancer. HER2 overexpr...

Descripción completa

Detalles Bibliográficos
Autores principales: Qian, Jing, Zhu, Weiyou, Wang, Keming, Ma, Lin, Xu, Jin, Xu, Tongpeng, Røe, Oluf Dimitri, Li, Aiping, Zhou, Jianwei, Shu, Yongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095045/
https://www.ncbi.nlm.nih.gov/pubmed/27167206
http://dx.doi.org/10.18632/oncotarget.9211