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JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients

BACKGROUND AND AIMS: JWA, a microtubule-associated protein (MAP) involved in apoptosis, has been identified as a suppressor of metastasis, and it affects cell migration in melanoma and its downregulation in tumor is an idependent negative prognostic factor in resectable gastric cancer. HER2 overexpr...

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Detalles Bibliográficos
Autores principales: Qian, Jing, Zhu, Weiyou, Wang, Keming, Ma, Lin, Xu, Jin, Xu, Tongpeng, Røe, Oluf Dimitri, Li, Aiping, Zhou, Jianwei, Shu, Yongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095045/
https://www.ncbi.nlm.nih.gov/pubmed/27167206
http://dx.doi.org/10.18632/oncotarget.9211

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