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Methylation-mediated repression of microRNA-129-2 suppresses cell aggressiveness by inhibiting high mobility group box 1 in human hepatocellular carcinoma

Aberrant expression of microRNAs (miRNAs) and its dysfunction have been revealed as crucial modulators of cancer initiation and progression. MiR-129-2 has been reported to play a tumor suppressive role in different human malignancies. Here, we demonstrated that miR-129-2 was significantly decreased...

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Detalles Bibliográficos
Autores principales: Liu, Zhikui, Dou, Changwei, Yao, Bowen, Xu, Meng, Ding, Linglong, Wang, Yufeng, Jia, Yuli, Li, Qing, Zhang, Hongyong, Tu, Kangsheng, Song, Tao, Liu, Qingguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095048/
https://www.ncbi.nlm.nih.gov/pubmed/27191994
http://dx.doi.org/10.18632/oncotarget.9377