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Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells

We recently reported the caspase3-dependent cleavage of Par-4 resulting in the accumulation of a 25kDa cleaved-Par-4 (cl-Par-4) fragment and we investigated in the present study the mechanisms regulating this fragment using cl-Par-4-expressing stable clones derived from ovarian and endometrial cance...

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Detalles Bibliográficos
Autores principales: Brasseur, Kevin, Fabi, François, Adam, Pascal, Parent, Sophie, Lessard, Laurent, Asselin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095052/
https://www.ncbi.nlm.nih.gov/pubmed/27175591
http://dx.doi.org/10.18632/oncotarget.9235