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Paracrine regulation of matrix metalloproteinases contributes to cancer cell invasion by hepatocellular carcinoma-secreted 14-3-3σ

14-3-3σ overexpression results in enhanced hepatocellular carcinoma (HCC) cell migration and HCC tumor vascular-invasion is significantly associated with 14-3-3σ expression. However, increased expression of 14-3-3σ paradoxically suppresses in vitro cell invasion of HCC. We hypothesize that surroundi...

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Detalles Bibliográficos
Autores principales: Liu, Chia-Chia, Chang, Tzu-Ching, Lin, Yi-Ting, Yu, Yen-Ling, Ko, Bor-Sheng, Sung, Li-Ying, Liou, Jun-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095053/
https://www.ncbi.nlm.nih.gov/pubmed/27175590
http://dx.doi.org/10.18632/oncotarget.9234