Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin

Proper control of cell-cell adhesion is crucial for embryogenesis and tissue homeostasis. In this study, we show that protein kinase C (PKC)δ, a member of the novel PKC subfamily, localizes at cell-cell contacts of epithelial cells through its C2-like domain in an F-actin-dependent manner. Upon hepa...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Lin, Wang, Shu-Hui, Chan, Po-Chao, Shen, Meng-Ru, Chen, Hong-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095074/
https://www.ncbi.nlm.nih.gov/pubmed/27203386
http://dx.doi.org/10.18632/oncotarget.9403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095074/
https://www.ncbi.nlm.nih.gov/pubmed/27203386
http://dx.doi.org/10.18632/oncotarget.9403

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