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Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin

Proper control of cell-cell adhesion is crucial for embryogenesis and tissue homeostasis. In this study, we show that protein kinase C (PKC)δ, a member of the novel PKC subfamily, localizes at cell-cell contacts of epithelial cells through its C2-like domain in an F-actin-dependent manner. Upon hepa...

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Detalles Bibliográficos
Autores principales:	Chen, Chien-Lin, Wang, Shu-Hui, Chan, Po-Chao, Shen, Meng-Ru, Chen, Hong-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095074/ https://www.ncbi.nlm.nih.gov/pubmed/27203386 http://dx.doi.org/10.18632/oncotarget.9403

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