Over-Expression of the Mycobacterial Trehalose-Phosphate Phosphatase OtsB2 Results in a Defect in Macrophage Phagocytosis Associated with Increased Mycobacterial-Macrophage Adhesion

Trehalose-6-phosphate phosphatase (OtsB2) is involved in the OtsAB trehalose synthesis pathway to produce free trehalose and is strictly essential for mycobacterial growth. We wished to determine the effects of OtsB2 expression on mycobacterial phenotypes such as growth, phagocytosis and survival in...

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Detalles Bibliográficos
Autores principales: Li, Hao, Wu, Mei, Shi, Yan, Javid, Babak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095139/
https://www.ncbi.nlm.nih.gov/pubmed/27867377
http://dx.doi.org/10.3389/fmicb.2016.01754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095139/
https://www.ncbi.nlm.nih.gov/pubmed/27867377
http://dx.doi.org/10.3389/fmicb.2016.01754

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