Overexpression of COP9 signalosome subunits, CSN7A and CSN7B, exerts different effects on adipogenic differentiation

The COP9 signalosome (CSN) is an essential regulator of cullin‐RING‐ubiquitin (Ub) ligases (CRLs), which ubiquitinate important cellular regulators and target them for degradation by the Ub proteasome system (UPS). The CSN exhibits deneddylating activity localized on subunit CSN5, which removes the...

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Detalles Bibliográficos
Autores principales: Huang, Xiaohua, Ordemann, Jürgen, Pratschke, Johann, Dubiel, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095148/
https://www.ncbi.nlm.nih.gov/pubmed/27833851
http://dx.doi.org/10.1002/2211-5463.12129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095148/
https://www.ncbi.nlm.nih.gov/pubmed/27833851
http://dx.doi.org/10.1002/2211-5463.12129

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