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Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank–Starling response

The Frank–Starling mechanism allows the amount of blood entering the heart from the veins to be precisely matched with the amount pumped out to the arterial circulation. As the heart fills with blood during diastole, the myocardium is stretched and oxidants are produced. Here we show that protein ki...

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Detalles Bibliográficos
Autores principales: Scotcher, Jenna, Prysyazhna, Oleksandra, Boguslavskyi, Andrii, Kistamas, Kornel, Hadgraft, Natasha, Martin, Eva D., Worthington, Jenny, Rudyk, Olena, Rodriguez Cutillas, Pedro, Cuello, Friederike, Shattock, Michael J., Marber, Michael S., Conte, Maria R., Greenstein, Adam, Greensmith, David J., Venetucci, Luigi, Timms, John F., Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095173/
https://www.ncbi.nlm.nih.gov/pubmed/27782102
http://dx.doi.org/10.1038/ncomms13187