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Evaluating frequency and quality of pathogen-specific T cells

It is generally accepted that enumeration and characterization of antigen-specific T cells provide essential information about potency of the immune response. Here, we report a new technique to determine the frequency and potency of antigen-specific CD8 T cells. The assay measures changes of intrace...

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Detalles Bibliográficos
Autores principales: Anikeeva, Nadia, Grosso, Dolores, Flomenberg, Neal, Sykulev, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095286/
https://www.ncbi.nlm.nih.gov/pubmed/27786275
http://dx.doi.org/10.1038/ncomms13264