Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane

The human YME1L protease is a membrane-anchored AAA+ enzyme that controls proteostasis at the inner membrane and intermembrane space of mitochondria. Understanding how YME1L recognizes substrates and catalyses ATP-dependent degradation has been hampered by the presence of an insoluble transmembrane...

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Detalles Bibliográficos
Autores principales: Shi, Hui, Rampello, Anthony J., Glynn, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095350/
https://www.ncbi.nlm.nih.gov/pubmed/27786171
http://dx.doi.org/10.1038/ncomms13301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095350/
https://www.ncbi.nlm.nih.gov/pubmed/27786171
http://dx.doi.org/10.1038/ncomms13301

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