Baclofen Protects Primary Rat Retinal Ganglion Cells from Chemical Hypoxia-Induced Apoptosis Through the Akt and PERK Pathways

Retinal ganglion cells (RGCs) consume large quantities of energy to convert light information into a neuronal signal, which makes them highly susceptible to hypoxic injury. This study aimed to investigate the potential protection by baclofen, a GABA(B) receptor agonist of RGCs against hypoxia-induce...

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Detalles Bibliográficos
Autores principales: Fu, Pingping, Wu, Qiang, Hu, Jianyan, Li, Tingting, Gao, Fengjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095369/
https://www.ncbi.nlm.nih.gov/pubmed/27867349
http://dx.doi.org/10.3389/fncel.2016.00255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095369/
https://www.ncbi.nlm.nih.gov/pubmed/27867349
http://dx.doi.org/10.3389/fncel.2016.00255

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