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Baclofen Protects Primary Rat Retinal Ganglion Cells from Chemical Hypoxia-Induced Apoptosis Through the Akt and PERK Pathways
Retinal ganglion cells (RGCs) consume large quantities of energy to convert light information into a neuronal signal, which makes them highly susceptible to hypoxic injury. This study aimed to investigate the potential protection by baclofen, a GABA(B) receptor agonist of RGCs against hypoxia-induce...
Autores principales: | Fu, Pingping, Wu, Qiang, Hu, Jianyan, Li, Tingting, Gao, Fengjuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095369/ https://www.ncbi.nlm.nih.gov/pubmed/27867349 http://dx.doi.org/10.3389/fncel.2016.00255 |
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