Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B

Widespread genetic modification of cells in the central nervous system (CNS) with a viral vector has become possible and increasingly more efficient. We previously applied an AAV9 vector with the cytomegalovirus/chicken beta-actin (CBA) hybrid promoter and achieved wide-scale CNS transduction in neo...

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Detalles Bibliográficos
Autores principales: Jackson, Kasey L., Dayton, Robert D., Deverman, Benjamin E., Klein, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095393/
https://www.ncbi.nlm.nih.gov/pubmed/27867348
http://dx.doi.org/10.3389/fnmol.2016.00116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095393/
https://www.ncbi.nlm.nih.gov/pubmed/27867348
http://dx.doi.org/10.3389/fnmol.2016.00116

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