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KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification

Lysine acetylation is a widespread post-translational modification regulating various biological processes. To characterize cellular functions of the human lysine acetyltransferases KAT2A (GCN5) and KAT2B (PCAF), we determined their acetylome by shotgun proteomics. One of the newly identified KAT2A/...

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Detalles Bibliográficos
Autores principales: Fournier, Marjorie, Orpinell, Meritxell, Grauffel, Cédric, Scheer, Elisabeth, Garnier, Jean-Marie, Ye, Tao, Chavant, Virginie, Joint, Mathilde, Esashi, Fumiko, Dejaegere, Annick, Gönczy, Pierre, Tora, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095585/
https://www.ncbi.nlm.nih.gov/pubmed/27796307
http://dx.doi.org/10.1038/ncomms13227