Gene therapy using plasmid DNA-encoded anti-HER2 antibody for cancers that overexpress HER2

Plasmid DNA-encoded antibodies, or DNA-based monoclonal antibodies (dMAbs), are delivered by intramuscular injection and in vivo electroporation (EP) and are effective in virus neutralization, although they have not been evaluated for tumor gene therapy. Here we investigated whether a dMAb was appro...

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Detalles Bibliográficos
Autores principales: Kim, H, Danishmalik, S N, Hwang, H, Sin, J-I, Oh, J, Cho, Y, Lee, H, Jeong, M, Kim, S-H, Hong, H J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095588/
https://www.ncbi.nlm.nih.gov/pubmed/27632934
http://dx.doi.org/10.1038/cgt.2016.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095588/
https://www.ncbi.nlm.nih.gov/pubmed/27632934
http://dx.doi.org/10.1038/cgt.2016.37

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