A self-assembling nanomedicine of conjugated linoleic acid-paclitaxel conjugate (CLA-PTX) with higher drug loading and carrier-free characteristic

The main objective of this study was to demonstrate the proof-of-principle for the hypothesis that conjugated linoleic acid-paclitaxel conjugate (CLA-PTX), a novel fatty acid modified anti-cancer drug conjugate, could self-assemble forming nanoparticles. The results indicated that a novel self-assem...

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Detalles Bibliográficos
Autores principales: Zhong, Ting, Yao, Xin, Zhang, Shuang, Guo, Yang, Duan, Xiao-Chuan, Ren, Wei, Dan Huang, Yin, Yi-Fan, Zhang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095675/
https://www.ncbi.nlm.nih.gov/pubmed/27812039
http://dx.doi.org/10.1038/srep36614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095675/
https://www.ncbi.nlm.nih.gov/pubmed/27812039
http://dx.doi.org/10.1038/srep36614

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