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OPN‐a induces muscle inflammation by increasing recruitment and activation of pro‐inflammatory macrophages

NEW FINDINGS: What is the central question of this study? What is the functional relevance of OPN isoform expression in muscle pathology? What is the main finding and its importance? The full‐length human OPN‐a isoform is the most pro‐inflammatory isoform in the muscle microenvironment, acting on ma...

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Detalles Bibliográficos
Autores principales: Many, Gina M., Yokosaki, Yasuyuki, Uaesoontrachoon, Kitipong, Nghiem, Peter P., Bello, Luca, Dadgar, Sherry, Yin, Ying, Damsker, Jesse M., Cohen, Heather B., Kornegay, Joe N., Bamman, Marcas M., Mosser, David M., Nagaraju, Kanneboyina, Hoffman, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095808/
https://www.ncbi.nlm.nih.gov/pubmed/27452303
http://dx.doi.org/10.1113/EP085768