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The Generation and Exploitation of Protein Mutability Landscapes for Enzyme Engineering

The increasing number of enzyme applications in chemical synthesis calls for new engineering methods to develop the biocatalysts of the future. An interesting concept in enzyme engineering is the generation of large‐scale mutational data in order to chart protein mutability landscapes. These landsca...

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Detalles Bibliográficos
Autores principales: van der Meer, Jan‐Ytzen, Biewenga, Lieuwe, Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095810/
https://www.ncbi.nlm.nih.gov/pubmed/27441919
http://dx.doi.org/10.1002/cbic.201600382