Cargando…
The Generation and Exploitation of Protein Mutability Landscapes for Enzyme Engineering
The increasing number of enzyme applications in chemical synthesis calls for new engineering methods to develop the biocatalysts of the future. An interesting concept in enzyme engineering is the generation of large‐scale mutational data in order to chart protein mutability landscapes. These landsca...
Autores principales: | van der Meer, Jan‐Ytzen, Biewenga, Lieuwe, Poelarends, Gerrit J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095810/ https://www.ncbi.nlm.nih.gov/pubmed/27441919 http://dx.doi.org/10.1002/cbic.201600382 |
Ejemplares similares
-
Using Mutability Landscapes To Guide Enzyme Thermostabilization
por: Guo, Chao, et al.
Publicado: (2020) -
Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases
por: van der Meer, Jan-Ytzen, et al.
Publicado: (2016) -
Tuning Enzyme Activity for Nonaqueous Solvents: Engineering an Enantioselective “Michaelase” for Catalysis in High Concentrations of Ethanol
por: Guo, Chao, et al.
Publicado: (2020) -
Selective Colorimetric “Turn-On”
Probe for Efficient Engineering
of Iminium Biocatalysis
por: Biewenga, Lieuwe, et al.
Publicado: (2020) -
Unlocking New Reactivities in Enzymes by Iminium Catalysis
por: Xu, Guangcai, et al.
Publicado: (2022)