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A kidney injury molecule‐1 (Kim‐1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells

BACKGROUND: Kidney injury molecule‐1 (Kim‐1) has been validated as a urinary biomarker for acute and chronic renal damage. The expression of Kim‐1 mRNA is also activated by acute kidney injury induced by cisplatin in rodents and humans. To date, the measurement of Kim‐1 expression has not fully allo...

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Detalles Bibliográficos
Autores principales: Kokura, Kenji, Kuromi, Yasushi, Endo, Takeshi, Anzai, Naohiko, Kazuki, Yasuhiro, Oshimura, Mitsuo, Ohbayashi, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095820/
https://www.ncbi.nlm.nih.gov/pubmed/27591740
http://dx.doi.org/10.1002/jgm.2925