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Chemical Platform for the Preparation of Synthetic Orally Active Peptidomimetics with Hemoregulating Activity
A novel chemical platform based on branched piperazine‐2,5‐dione derivatives (2,5‐diketopiperazines) for creating orally available biologically active peptidomimetics has been developed. The platform includes a diketopiperazine scaffold with “built‐in” functionally active peptide fragments covalentl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095862/ https://www.ncbi.nlm.nih.gov/pubmed/27457274 http://dx.doi.org/10.1002/cmdc.201600157 |