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Targeting of the P2X7 receptor in pancreatic cancer and stellate cells

The ATP‐gated receptor P2X7 (P2X7R) is involved in regulation of cell survival and has been of interest in cancer field. Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer and new markers and therapeutic targets are needed. PDAC is characterized by a complex tumour microenvironment, which in...

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Detalles Bibliográficos
Autores principales: Giannuzzo, Andrea, Saccomano, Mara, Napp, Joanna, Ellegaard, Maria, Alves, Frauke, Novak, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095874/
https://www.ncbi.nlm.nih.gov/pubmed/27513892
http://dx.doi.org/10.1002/ijc.30380