Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma

Cell free DNA (cfDNA) has received increasing attention and has been studied in a broad range of clinical conditions. However, few studies have focused on mitochondrial DNA (mtDNA) in the cell free form. We optimized DNA isolation and sequencing library preparation protocols to better retain short D...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Ruoyu, Nakahira, Kiichi, Guo, Xiaoxian, Choi, Augustine M.K., Gu, Zhenglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095883/
https://www.ncbi.nlm.nih.gov/pubmed/27811968
http://dx.doi.org/10.1038/srep36097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095883/
https://www.ncbi.nlm.nih.gov/pubmed/27811968
http://dx.doi.org/10.1038/srep36097

Ejemplares similares