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Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma
Cell free DNA (cfDNA) has received increasing attention and has been studied in a broad range of clinical conditions. However, few studies have focused on mitochondrial DNA (mtDNA) in the cell free form. We optimized DNA isolation and sequencing library preparation protocols to better retain short D...
Autores principales: | Zhang, Ruoyu, Nakahira, Kiichi, Guo, Xiaoxian, Choi, Augustine M.K., Gu, Zhenglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095883/ https://www.ncbi.nlm.nih.gov/pubmed/27811968 http://dx.doi.org/10.1038/srep36097 |
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