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Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress
Nucleolar proteins play an important role in the regulation of the MDM2–p53 pathway, which coordinates cellular response to stress. However, the mechanism underlying this regulation remains poorly understood. Here, we report that the nucleolar protein CSIG is a novel and crucial regulator of the MDM...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095888/ https://www.ncbi.nlm.nih.gov/pubmed/27811966 http://dx.doi.org/10.1038/srep36171 |