Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress

Nucleolar proteins play an important role in the regulation of the MDM2–p53 pathway, which coordinates cellular response to stress. However, the mechanism underlying this regulation remains poorly understood. Here, we report that the nucleolar protein CSIG is a novel and crucial regulator of the MDM...

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Detalles Bibliográficos
Autores principales: Xie, Nan, Ma, Liwei, Zhu, Feng, Zhao, Wenhui, Tian, Feng, Yuan, Fuwen, Fu, Jingxuan, Huang, Daoyuan, Lv, Cuicui, Tong, Tanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095888/
https://www.ncbi.nlm.nih.gov/pubmed/27811966
http://dx.doi.org/10.1038/srep36171

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