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The unconventional kinetoplastid kinetochore: from discovery toward functional understanding
The kinetochore is the macromolecular protein complex that drives chromosome segregation in eukaryotes. Its most fundamental function is to connect centromeric DNA to dynamic spindle microtubules. Studies in popular model eukaryotes have shown that centromere protein (CENP)-A is critical for DNA-bin...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Portland Press Ltd.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095916/ https://www.ncbi.nlm.nih.gov/pubmed/27911702 http://dx.doi.org/10.1042/BST20160112 |